In short, I could resolve the issue as follows: (1) Create a file user-config.jam in the boost root with the following contents: using darwin : std0x : "/opt/local/bin/g++" : <cxxflags>-std=gnu++0x ; (2) Because non-Apple versions of g++ do not support -no-cpp-precomp, we need to remove this option in file tools/build/v2/tools/darwin.jam. In line 485, change flags darwin.compile OPTIONS : -no-cpp-precomp -gdwarf-2 ; to flags darwin.compile OPTIONS : -gdwarf-2 ; (3) Now build Boost with ./bootstrap.sh ./bjam --with-toolset=darwin-std0x Obviously this is not a clean solution, but my Boost Build knowledge is quite limited to come up with the right approach. What would be the right way to do fix this? Matthias